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ESI-09
Artikelnummer: Cay19130-10
Exchange protein activated by cAMP (Epac) proteins mediate cAMP signaling independent of protein kinase A (PKA). ESI-09 is an inhibitor of Epac1 and Epac2 with IC50 values of 3.2 and 1.4 µM, respectively. It shows no activity against PKA at concentrations as high as 25 µM. ESI-09 has been shown to block Akt...
| Schlagworte: | alpha-[2-(3-chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-beta-oxo-3-isoxazolepropanenitrile |
| Anwendung: | Epac1 / Epac2 inhibitor |
| CAS | 263707-16-0 |
| MW: | 330.8 D |
ab 44,00 €
ESI-09
Artikelnummer: TGM-T2244-100mg
Description: ESI-09 is a new-typel noncyclic nucleotide EPAC antagonist.The IC50 values of ESI-09 for EPAC1 and EPAC2 is 3.2 and 1.4 µM, respectively. Target: cAMP, Virus Protease. Smiles: CC(C)(C)c1cc(no1)C(=O)C(=NNc1cccc(Cl)c1)C#N. References: Almahariq M , et al. Mol Pharmacol. 2013, 83(1), 122-128.
| Anwendung: | Epac1 / Epac2 inhibitor |
| CAS | 263707-16-0 |
| MW: | 330.77 D |
ab 37,00 €
