Zu "2549174-42-5" wurden 2 Artikel gefunden!
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FGFR2-IN-3
Artikelnummer: TGM-T60185-100mg
Description: FGFR2-IN-3 is an orally active selective FGFR2 inhibitor[1]. Target: FGFR. Smiles: CC(=C)C(=O)Nc1ccc(cc1)-c1c(-c2ccc(Oc3nccc(C)n3)c(F)c2)c2c(N)ncnc2n1C. References: Lescarbeau, Andre, et al. Preparation of substituted pyrrolopyrimidines as FGFR inhibitors and methods of making and using the same....
| Anwendung: | Targets fibroblast growth factor receptor 2 [EC:2.7.10.1] (FGFR2, CD332) |
| CAS | 2549174-42-5 |
| MW: | 509.53 D |
ab 82,00 €
Lirafugratinib
Artikelnummer: Cay40940-1
A covalent FGFR2 inhibitor (IC50 = 0.003 µM), selective for FGFR2 over FGFR1, -3, and -4 (IC50s = 0.77, 0.26, and 15 µM, respectively), inhibits the proliferation of SNU-16 cells (IC50 = 0.002 µM), reduces intratumoral FGFR2 phosphorylation and tumor volume in an FGFR2-amplified SNU-16 gastric cancer mouse xenograft...
| Schlagworte: | RLY-4008,... |
| Anwendung: | Covalent FGFR2 inhibitor |
| CAS | 2549174-42-5 |
| MW: | 509.5 D |
ab 55,00 €
