Zu "253863-19-3" wurden 2 Artikel gefunden!
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(5Z)-7-Oxozeaenol
Artikelnummer: Cay17459-5
(5Z)-7-Oxozeaenol is a resorcylic acid lactone fungal metabolite and an inhibitor of TGF-beta activated kinase 1 (TAK1, IC50 = 8.1 nM in the presence of TAK1-binding protein 1 (TAB1)). It is selective for TAK1 over MEK1 and MEKK1 (IC50s = 411 and 268 nM, respectively), as well as apoptosis signal-regulating kinase 1...
| Schlagworte: | FR148083, L-783,279, LL-Z 1640-2,... |
| Anwendung: | TAK1 inhibitor |
| CAS | 253863-19-3 |
| MW: | 362.4 D |
ab 133,00 €
5Z-7-Oxozeaenol
Artikelnummer: TGM-T14055-1mg
Description: 5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-beta-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is also an inhibitor of VEGF-R2 with IC50 of 52 nM. Target: MAPK, MEK, FLT,...
| Schlagworte: | FR148083, L783279, LL-Z 1640-2 |
| Anwendung: | TAK1 inhibitor |
| CAS | 253863-19-3 |
| MW: | 362.37 D |
ab 307,00 €
