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CP 547,632
Artikelnummer: Cay21773-1
CP 547,632 is an orally bioavailable and potent inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and basic fibroblast growth factor (bFGF) with IC50 values of 11 and 9 nM, respectively, in an enzyme assay. It is selective for VEGFR2 and bFGF over EGFR, PDGF receptor beta (PDGFRbeta), and related...
| Schlagworte: | 3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-[[[[4-(1-pyrrolidinyl)butyl]amino]carbonyl]amino]-4-isothiazolecarboxamide |
| Anwendung: | VEGFR2 inhibitor |
| CAS | 252003-65-9 |
| MW: | 532.4 D |
ab 89,00 €
CP-547632
Artikelnummer: TGM-T10870L-10mg
Description: CP-547632 is an orally available and potent, ATP-competitive dual inhibitor of VEGFR-2 and FGF kinase F with IC50s of 11 nM and 9 nM, respectively. CP-547632 is selective, with higher selectivity for VEGFR2 and bFGF than for EGFR, PDGFRbeta and related tyrosine kinases (TKs). PDGFRbeta and related...
| CAS | 252003-65-9 |
| MW: | 532.4 D |
ab 30,00 €
