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CFT7455
Artikelnummer: TGM-T60024-10mg
Description: CFT7455 (Cemsidomide) is an anti-cancer agent showing high affinity to the cereblon E3 ligase with a Kd of 0.9 nM. CFT7455 is an orally active degrader of zinc finger transcription factors Ikaros (IKZF1), and Aiolos (IKZF3). Target: Ligand for E3 Ligase. Smiles:...
| Schlagworte: | Cemsidomide |
| Anwendung: | Protac(R) reagent |
| CAS | 2504235-67-8 |
| MW: | 469.53 D |
ab 75,00 €
CFT7455
Artikelnummer: BPS-82010
CFT7455 is an anti-cancer agent that binds with high affinity to the cereblon E3 ligase.
| Anwendung: | Protac(R) reagent |
| CAS | 2504235-67-8 |
| MW: | 469,5 D |
2.100,00 €
CFT-7455
Artikelnummer: Cay42053-1
A cereblon ligand 1-containing degrader of IKZF1 and IKZF3, reduces levels of IKZF1 and IKZF3 in NCI H929 cells at 0.1 nM, decreases the growth of NCI H929 cells (GI50 = 0.0743 nM), reduces tumor volume in an RPMI-8226 plasmocytoma mouse xenograft model at 30 or 100 µg/kg per day. Formulation: A solid. InChI:...
| Schlagworte: | Cemsidomide, 3S-[6-[[4-(4-morpholinylmethyl)phenyl]methyl]-2-oxobenz[cd]indol-1(2H)-yl]-2,6-piperidinedione |
| Anwendung: | Cereblon ligand 1-containing IKZF1 / IKZF3 degrader |
| CAS | 2504235-67-8 |
| MW: | 469.53 D |
ab 110,00 €
