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BIM-46187 (hydrochloride)
Artikelnummer: Cay34531-1
BIM-46187 is an inhibitor of heterotrimeric G-protein signaling. It inhibits signaling through Galphai, Galphas, and Galphaq in MZ7 cells but selectively inhibits Galphaq in HEK293 and CHO cells, indicating cell-dependent inhibition. BIM-46187 (0.1-1 mg/kg) increases the paw withdrawal threshold to a mechanical...
| Schlagworte: | (2R,2'R)-3,3'-dithiobis[2-amino-1-[(8S)-8-(cyclohexylmethyl)-5,6-dihydro-2-phenylimidazo[1,2-a]pyrazin-7(8H)-yl]-1-propano... |
| Anwendung: | Heterotrimeric G-protein signaling inhibitor |
| CAS | 2489449-03-6 |
| MW: | 940.9586 D |
ab 76,00 €
BIM-46187 4HCl
Artikelnummer: TGM-T16519L-100mg
Description: BIM-46187 4HCl (PH-064 4HCl) is a heterotrimeric G-protein complex inhibitor. Target: Others. Smiles: O=C([C@@H](N)CSSC[C@H](N)C(N(CCN1C2=NC(C3=CC=CC=C3)=C1)[C@H]2CC4CCCCC4)=O)N5[C@H](C6=NC(C7=CC=CC=C7)=CN6CC5)CC8CCCCC8.Cl.Cl.Cl.Cl. References: Favre-Guilmard C, et al. The novel inhibitor of the...
| Schlagworte: | PH-064 4HCl |
| Anwendung: | Heterotrimeric G-protein signaling inhibitor |
| CAS | 2489449-03-6 |
| MW: | 940.95 D |
ab 138,00 €
