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AXC-715 (hydrochloride)
AXC-715 (hydrochloride)

Artikelnummer: Cay44007-1

AXC-715 is a dual agonist of toll-like receptor 7 (TLR7) and TLR8. It activates NF-kappaB in a secreted alkaline phosphatase (SEAP) assay using TLR7- or TLR8-expressing HEK293 cells (EC50s = 0.634 and 1.3 µM, respectively). AXC-715 has been linked to the anti-HER2 antibody trastuzumab as an antibody-drug conjugate...
Schlagworte: T785, 4-amino-2-butyl-1H-imidazo[4,5-c]quinoline-1-butanamine, trihydrochloride
Anwendung: TLR7 / TLR8 dual agonist
CAS 2479276-17-8
MW: 420.8 D
ab 147,00 €
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AXC-715 trihydrochloride
AXC-715 trihydrochloride

Artikelnummer: TGM-T72253-100mg

Description: AXC-715 trihydrochloride (T785 trihydrochloride) is a TLR7/TLR8 dual agonist for the synthesis of antibody-adjuvanted immunocouplings. The couplings are mostly programmed death ligand 1 (PD-L1) attached to one or more antibody structures of the adjuvant. Target: TLR. Smiles:...
Schlagworte: T785 trihydrochloride
CAS 2479276-17-8
MW: 420.81 D
ab 81,00 €
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