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Dexrazoxane
Dexrazoxane

Artikelnummer: Cay14632-5

Dexrazoxane is an intracellular iron chelator and an inhibitor of topoisomerase IIalpha. Through these activities, dexazoxane is highly protective in reducing anthracycline-induced cardiotoxicity and extravasation injury. Dexrazoxane has also been shown to act as an antioxidant that scavenges hydroxyl (IC50 = 2.1...
Schlagworte: ICRF 187, NSC 169780, Totect(R), Zinecard, 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-2,6-piperazinedione
CAS 24584-09-6
MW: 268.3 D
ab 44,00 €
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Dexrazoxane
Dexrazoxane

Artikelnummer: LKT-D1994.100

Dexrazoxane is an iron chelator that exhibits cardioprotective, antioxidative, pro-angiogenic, and anti-parasitic activities. Dexrazoxane decreases superoxide formation and prevents anthracycline-induced cardiotoxicity. In animal models of myocardial infarction, dexrazoxane decreases infarct size, increases...
Anwendung: Cardioprotectant, Iron chelator, Antioxidant
CAS 24584-09-6
MW: 268.27 D
ab 109,00 €
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Dexrazoxane
Dexrazoxane

Artikelnummer: TGM-T22305-100mg

Description: Dexrazoxane (ICRF-187) is an anticancer drug used to block mitosis and arrest dividing cells. It is an iron chelator and provides cardioprotection against anthracycline toxicity. Target: Others. Smiles: C[C@@H](CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1. References: Jones, R.L., Utility of dexrazoxane for the...
Schlagworte: ICRF-187
Anwendung: Targets DNA topoisomerase II [EC:5.6.2.2] (TOP2)
CAS 24584-09-6
MW: 268.27 D
ab 40,00 €
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