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FSLLRY-NH2
Artikelnummer: TGM-TP1904-10mg
Description: Selective PAR2 peptide antagonist. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch. References: McLarty et...
| Anwendung: | PAR2 antagonist |
| CAS | 245329-02-6 |
| MW: | 796.97 D |
ab 222,00 €
FSLLRY-amide
Artikelnummer: Cay14709-5
FSLLRY-amide is a peptide antagonist of protease-activated receptor (PAR) 2 which blocks activation by trypsin (IC50 = ~50 µM) but not by the synthetic agonist SLIGRL-NH2 (Cay-16723). It does not affect thrombin-induced activation of PAR1 or trypsin-mediated proteolysis of casein. It can be used to study PAR2 action...
| Schlagworte: | L-phenylalanyl-L-seryl-L-leucyl-L-leucyl-L-arginyl-L-tyrosinamide |
| Anwendung: | PAR2 antagonist |
| CAS | 245329-02-6 |
| MW: | 797 D |
ab 122,00 €
