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NEU
NV03
Artikelnummer: Cay45383-1
NV03 is an inhibitor of the protein-protein interaction between E3 ubiquitin-protein ligase UHRF1 (UHRF1) and histone H3 trimethylated lysine 9 (H3K9Me3). It binds the tandem Tudor domain (TTD) of UHRF1 (Kd = 2.4 µM) and is selective for the UHRF1-TTD over a panel of 36 demethylases at 10 µM.. SMILES:...
| Schlagworte: | N-[3-(diethylamino)propyl]-5,9-dimethyl-8-oxo-thieno[2',3':4,5]pyrrolo[1,2-d][1,2,4]triazine-7(8H)-acetamide |
| Anwendung: | UHRF1-H3K9Me3 protein-protein interaction inhibitor |
| CAS | 2448341-58-8 |
| MW: | 389.52 D |
ab 139,00 €
NV03
Artikelnummer: TGM-T12271-25mg
Description: NV03 is a potent and selective antagonist of the UHRF1 (Ubiquitin-like with PHD and RING finger domains 1)-H3K9me3 interaction, binding to the UHRF1 tandem tudor domain with a Kd of 2.4 µM. NV03 holds potential as an anticancer therapeutic [1]. Target: Others. Smiles:...
| CAS | 2448341-58-8 |
| MW: | 389.52 D |
1.289,00 €
