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DS16570511
Artikelnummer: Cay24160-1
DS16570511 is an inhibitor of the mitochondrial calcium uniporter. It inhibits calcium uptake by mitochondria isolated from HEK293A cells, rat heart, and pig heart (IC50s = 0.86, 25, and 15 µM, respectively). DS16570511 inhibits fetal bovine serum-induced mitochondrial calcium influx as well as MCU- and...
| Schlagworte: | 3-[3-[[[3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]methyl]amino]benzoyl]-1H-indole-1-butanoic acid |
| Anwendung: | Mitochondrial calcium uniporter inhibitor |
| CAS | 2446154-84-1 |
| MW: | 562.4 D |
ab 95,00 €
DS16570511
Artikelnummer: TGM-T11102-100mg
Description: DS16570511 is a novel, cell-permeable inhibitor targeting the mitochondrial calcium uniporter. It effectively blocks the increase in Ca2+ influx dependent on MCU or MICU1 [1]. Target: Calcium Channel. Smiles: C(=O)(C=1C=2C(N(CCCC(O)=O)C1)=CC=CC2)C3=CC(NCC=4C(=NOC4C)C5=C(Cl)C=CC=C5Cl)=CC=C3. References:...
| CAS | 2446154-84-1 |
| MW: | 562.44 D |
ab 243,00 €
