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IHMT-MST1-58
Artikelnummer: Cay43664-1
IHMT-MST1-58 is an inhibitor of mammalian Ste20-like protein kinase 1 (MST1, IC50 = 23 nM). It is selective for MST1 over MST2 and NIMA-related kinase 3 (NEK3, IC50s = 652 and >10,000 nM, respectively). IHMT-MST1-58 (50 mg/kg per day) reduces fasting blood glucose levels in mice in models of type 1- or type 2...
| Schlagworte: | 4-[[5,6,7,8-tetrahydro-5,8-dimethyl-7-(2-methylphenyl)-6-oxo-2-pteridinyl]amino]-benzenesulfonamide |
| Anwendung: | MST1 inhibitor |
| CAS | 2414484-25-4 |
| MW: | 438.51 D |
ab 85,00 €
IHMT-MST1-58
Artikelnummer: TGM-T62512-100mg
Description: IHMT-MST1-58 is a STE20-like protein 1 kinase (MST1) inhibitor (IC50:23 nM) with high efficiency, selectivity and oral activity. IHMT-MST1-58 can be used to study type 1 or type 2 diabetes. Target: Hippo pathway. Smiles: CN1C=2C(N(C)C(=O)C1C3=C(C)C=CC=C3)=CN=C(NC4=CC=C(S(N)(=O)=O)C=C4)N2. References: Wu...
| CAS | 2414484-25-4 |
| MW: | 438.5 D |
ab 91,00 €
