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DC-U4106
Artikelnummer: TGM-T63685-100mg
Description: DC-U4106 is a USP8-targeted inhibitor (Kd: 4.7 µM, IC50: 1.2 µM). DC-U4106 can use the ubiquitination pathway to promote the degradation of Eralpha. DC-U4106 inhibits the growth of tumor cells with low toxicity and can be used to study breast cancer. Target: Others. Smiles:...
| CAS | 2410534-62-0 |
| MW: | 525.56 D |
ab 3.766,00 €
DC-U4106
Artikelnummer: Cay41723-1
A USP8 inhibitor (IC50 = 1.2 µM), selective for USP8 over USP2 and USP7 (IC50s = 58.4 and >100 µM, respectively), induces apoptosis in, and inhibits colony formation by, MCF-7 cells from 1-5 µM, reduces tumor volume in an MCF-7 mouse xenograft model at 20 mg/kg. Formulation: A solid. InChI:...
| Schlagworte: | 8-[(3,5-dimethyl-1H-pyrazol-4-yl)oxy]-5,7-dihydroxy-2-[4-[4-(2-pyridinyl)-1-piperazinyl]phenyl]-4H-1-benzopyran-4-one |
| Anwendung: | USP8 inhibitor |
| CAS | 2410534-62-0 |
| MW: | 525.6 D |
ab 223,00 €
