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RIPK2 Inhibitor OD36 (hydrochloride)
Artikelnummer: Cay42171-5
A RIPK2 inhibitor (IC50 = 5.3 nM), inhibits wild-type and R206H mutant ALK2 (IC50s = 47 and 22 nM, respectively), inhibits activin A-induced chondrogenic and osteogenic differentiation in ATDC-5 cells overexpressing ALKR206H at 0.5 µM, reduces the number of peritoneal lavage neutrophils and lymphocytes in a mouse...
| Schlagworte: | OD36, Receptor-interacting Serine/Threonine Kinase 2 Inhibitor OD36,... |
| Anwendung: | RIPK2 inhibitor |
| CAS | 2387510-88-3 |
| MW: | 367.2 D |
ab 58,00 €
OD36 hydrochloride
Artikelnummer: TGM-T61424-100mg
Description: OD36 hydrochloride (OD-36 hydrochloride) is a potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 hydrochloride is a macrocyclic inhibitor that binds efficiently to the ATP pocket of the ALK2 kinase and effectively antagonizes mutant ALK2 signaling and osteogenic differentiation.OD36 hydrochloride...
| Schlagworte: | OD-36 hydrochloride, OD 36 hydrochloride |
| CAS | 2387510-88-3 |
| MW: | 367.23 D |
ab 1.222,00 €
