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Autogramin-2
Autogramin-2

Artikelnummer: Cay43556-10

Autogramin-2 is an inhibitor of Aster-A (IC50 = 1. µM), a protein that transports cholesterol from the plasma membrane to the endoplasmic reticulum (ER). Autogramin-2 is selective for Aster-A over Aster-B and -C (IC50s = >20 µM for both). It inhibits autophagy induced by amino acid starvation or rapamycin-mediated...
Schlagworte: 6,7-dihydro-2-[[4-(1-methylethoxy)benzoyl]amino]-thiazolo[5,4-c]pyridine-5(4H)-carboxylic acid, 1,1-dimethylethyl ester
Anwendung: Aster-A (GRAMD1A) inhibitor
CAS 2375541-45-8
MW: 417.52 D
ab 85,00 €
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Autogramin-2
Autogramin-2

Artikelnummer: TGM-T9013-100mg

Description: Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by either starvation with IC50 of 0.27 µM, and inhibits mTORC1 (Rapamycin, IC50:0.14 µM). Target: Autophagy. Smiles:...
Schlagworte: tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate
CAS 2375541-45-8
MW: 417.52 D
ab 37,00 €
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