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DS12881479
Artikelnummer: Cay44121-1
DS12881479 is an inhibitor of MAP kinase-interacting serine/threonine protein kinase 1 (MNK1, IC50s = 21 and 416 nM for the inactive and active forms, respectively). It is selective for MNK1 over 46 other kinases but does inhibit FMS-related tyrosine kinase 3 (FLT3) and dual-specificity tyrosine...
| Schlagworte: | 1-methyl-N-(5-phenyl-2-thiazolyl)-4-piperidinecarboxamide |
| Anwendung: | MNK1 (MKNK1) inhibitor |
| CAS | 2373065-59-7 |
| MW: | 301.41 D |
ab 172,00 €
DS12881479
Artikelnummer: TGM-T60681-10mg
Description: DS12881479 can be used in cancer research which is a potent and selective inhibitor of Mnk1(IC 50 =21 nM) [1]. Target: MNK. Smiles: CN1CCC(CC1)C(=O)Nc1ncc(s1)-c1ccccc1. References: Yumi Matsui, et al. A novel inhibitor stabilizes the inactive conformation of MAPK-interacting kinase 1. Acta Crystallogr F...
| CAS | 2373065-59-7 |
| MW: | 301.41 D |
ab 95,00 €
