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NVS-ZP7-4
Artikelnummer: Cay33773-1
NVS-ZP7-4 is an inhibitor of the zinc transporter SLC39A7 (ZIP7). It induces apoptosis in TALL-1 human T cell acute lymphoblastic leukemia cells, an effect that can be reduced by expression of the ZIP7 point mutant ZIP7V430E. NVS-ZP7-4 (20 µM) increases endoplasmic reticulum, but not cytosolic, zinc levels in U2OS...
| Schlagworte: | 1-[(2S)-2-[(6-fluoro-2-benzothiazolyl)amino]-3-phenylpropyl]-spiro[piperidine-4,4'(1'H)-quinazolin]-2'(3'H)-one |
| Anwendung: | ZIP7 inhibitor |
| CAS | 2349367-89-9 |
| MW: | 501.6 D |
ab 93,00 €
NVS-ZP7-4
Artikelnummer: TGM-T12277-100mg
Description: NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7). Target: Others. Smiles: Fc1ccc2nc(N[C@H](CN3CCC4(CC3)NC(=O)Nc3ccccc43)Cc3ccccc3)sc2c1. References: Nolin E, et al. Discovery of a ZIP7 inhibitor from a Notch pathway screen. Nat Chem Biol. 2019 Feb,15(2):179-188.
| Anwendung: | ZIP7 inhibitor |
| CAS | 2349367-89-9 |
| MW: | 501.62 D |
ab 61,00 €
