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Ceapin-A7
Artikelnummer: TGM-T9110-5mg
Description: Ceapin-A7, with an IC50 of 0.59 µM, selectively inhibits ATF6alpha signaling in response to ER stress. This compound is instrumental in investigating ATF6alpha's activation mechanism and its function in pathological conditions. Target: Others. Smiles:...
| Anwendung: | ATF6alpha inhibitor |
| CAS | 2323027-38-7 |
| MW: | 470.32 D |
ab 38,00 €
Ceapin-A7
Artikelnummer: Cay36113-5
Ceapin-A7 is an inhibitor of activating transcription factor 6alpha (ATF6alpha, IC50 = 0.59 µM in a reporter assay). It is selective for ATF6alpha over ATF6beta at 18.9 µM. Ceapin-A7 (6 µM) sensitizes U2OS osteosarcoma cells to the sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA) inhibitor and ER stress...
| Schlagworte: | N-[1-[[2,4-bis(trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-5-(2-furanyl)-3-isoxazolecarboxamide |
| Anwendung: | ATF6alpha inhibitor |
| CAS | 2323027-38-7 |
| MW: | 470.3 D |
ab 69,00 €
