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SRI-37330
SRI-37330

Artikelnummer: TGM-T60004-100mg

Description: SRI-37330 inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. Target: Others. Smiles: CS(=O)(=O)NCC1CCCN(C1)c1ncnc2ccc(cc12)C(F)(F)F. References: Thielen LA, et al. Identification of an Anti-diabetic, Orally Available Small Molecule that...
Anwendung: TXNIP inhibitor
CAS 2322245-42-9
MW: 388.41 D
ab 52,00 €
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SRI-37330
SRI-37330

Artikelnummer: Cay31638-1

SRI-37330 is an inhibitor of thioredoxin-interacting protein (TXNIP). It inhibits the expression of Txnip mRNA in INS-1 rat insulinoma cells (IC50 = 0.64 µM) and decreases Txnip protein levels in the same cells in a concentration-dependent manner. SRI-37330 (10 µM) inhibits LPS-induced pyroptosis in A549 cells...
Schlagworte: N-[[1-[6-(trifluoromethyl)-4-quinazolinyl]-3-piperidinyl]methyl]-methanesulfonamide
Anwendung: TXNIP inhibitor
CAS 2322245-42-9
MW: 388.4 D
ab 40,00 €
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