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LEI110
Artikelnummer: TGM-T9753-10mg
Description: LEI110 is a potent Phospholipase A2, group XVI (PLA2G16) inhibitor with an Ki value of 20 nM. LEI110 is a selective pan-inhibitor of the HRASLS family of thiol hydrolases (i.e., PLA2G16, HRASLS2, RARRES3 and iNAT). Target: Phospholipase. Smiles: FC(F)(F)c1ccc(Oc2ccc(CCNC(=O)C(=O)CCCc3ccccc3)cc2)nc1....
| Anwendung: | PLAAT3 (AdPLA) inhibitor |
| CAS | 2313525-90-3 |
| MW: | 456.46 D |
ab 91,00 €
LEI-110
Artikelnummer: Cay36789-1
LEI-110 is an inhibitor of adipose phospholipase A2 (AdPLA2, IC50 = 100 nM). It also inhibits HRas-like suppressor 2 (HRASL2), retinoid acid receptor responder protein 3 (RARRES3), and calcium-independent N-acyltransferase (iNAT, IC50s = 158, 158, and 25 nM, respectively). LEI-110 (10 µM) decreases arachidonic acid...
| Schlagworte: | alpha-oxo-N-[2-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]ethyl]-benzenepentanamide |
| Anwendung: | PLAAT3 (AdPLA) inhibitor |
| CAS | 2313525-90-3 |
| MW: | 456.5 D |
ab 120,00 €
