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Lapatinib
Artikelnummer: Cay11493-10
Lapatinib is a dual inhibitor of the EGF receptor (EGFR) and ErbB2 (IC50s = 19 and 3 nM, respectively). It inhibits the growth of EGFR-overexpressing A431 skin cancer and ErbB2-overexpressing SK-BR-3 breast cancer cells (IC50s = 0.14 and 0.124 µM, respectively). Lapatinib also inhibits the growth of ErbB2-amplified...
| Schlagworte: | GSK 572016, GW 572016,... |
| Anwendung: | EGFR / HER2 inhibitor |
| CAS | 231277-92-2 |
| MW: | 581.1 D |
ab 77,00 €
Lapatinib, Free Base (GSK 572016, GW-572016, GW 572016X,...
Artikelnummer: LC-L-4899_500mg
Soluble in DMSO at 200 mg/mL, very poorly soluble in ethanol, very poorly soluble in water, maximum solubility in plain water is estimated to be about 1-10 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
| Schlagworte: | GSK572016, GW 572016, Tyverb,... |
| Anwendung: | EGFR / HER2 inhibitor |
| CAS | 231277-92-2 |
| MW: | 581,06 D |
ab 76,00 €
![Lapatinib, Free Base (N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl](https://www.biomol.com/media/image/7a/bd/d9/L1315-51-100_200x200.jpg "Lapatinib, Free Base (N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl")
Lapatinib, Free Base...
Artikelnummer: L1315-51.100
ATP-competitive EGFR & ErbB-2 dual tyrosine kinase inhibitor. Lapatinib is an ATP-competitive epidermal growth factor receptor (EGFR) and HER2/neu (ErbB-2) dual tyrosine kinase inhibitor, with IC(50) values of 10.8 and 9.2nm respectively. It is an orally active drug for treatment of breast cancer and other solid...
| CAS | 231277-92-2 |
| MW: | 581.06 |
210,00 €
Lapatinib
Artikelnummer: SYN-1052-M001
Soluble in DMSO or ethanol. Lapatinib is an ATP-competitive epidermal growth factor receptor (EGFR) and HER2/neu (ErbB-2) dual tyrosine kinase inhibitor, with IC(50) values of 10.8 and 9.2nM respectively. It is an orally active drug for treatment of breast cancer and other solid tumors. Target: EGFR , Kinase...
| Schlagworte: | GW-572016 |
| Anwendung: | EGFR / ErbB2 inhibitor |
| CAS | 231277-92-2 |
| MW: | 581,1 D |
ab 66,00 €
Lapatinib free base
Artikelnummer: LKT-L0362.100
Inhibitor of EGFR/HER2 (ErbB2).
| Schlagworte: | GSK572016, GW572016 |
| Anwendung: | EGFR tyrosine kinase inhibitor, ERBB2 tyrosine kinase inhibitor |
| CAS | 231277-92-2 |
| MW: | 581.06 D |
ab 76,00 €
