Zu "2306178-56-1" wurden 2 Artikel gefunden!
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DMX-5084
Artikelnummer: Cay42334-10
A MAP4K4 inhibitor (IC50 = 3 nM), selective for MAP4K4 over a panel of 141 kinases at 1 µM but does inhibit MAP4K6 and TNIK (IC50s = 6.61 and 10.96 nM, respectively), prevents hydrogen peroxide-induced decreases in viability in vCor.4U cells (EC50 = 3.16 nM), inhibits menadione-induced decreases in the OCR and ECAR...
| Schlagworte: | 3,7-dihydro-5-[4-(2-methoxyethoxy)phenyl]-7-phenyl-4H-pyrrolo[2,3-d]pyrimidin-4-one |
| Anwendung: | MAP4K4 (HGK) inhibitor |
| CAS | 2306178-56-1 |
| MW: | 361.39 D |
ab 112,00 €
DMX-5804
Artikelnummer: TGM-T5483-100mg
Description: DMX-5804 is a potent, selective MAP4K4 inhibitor, with an IC50 of 3 nM.DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice. Target: MAPK. Smiles: COCCOc1ccc(cc1)-c1cn(-c2ccccc2)c2nc[nH]c(=O)c12. References: Fiedler LR, et al. MAP4K4 Inhibition Promotes Survival of...
| Schlagworte: | DMX-5084 |
| CAS | 2306178-56-1 |
| MW: | 361.39 D |
ab 102,00 €
