Zu "2301866-59-9" wurden 2 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
DO264
Artikelnummer: Cay29402-1
DO264 is an inhibitor of alpha/beta-hydrolase domain-containing protein 12 (ABHD12, IC50 = 11 nM). It inhibits ABHD12-dependent hydrolysis of lysophosphatidylserine (lyso-PS) in mouse brain membrane lysates (IC50 = 2.8 nM) and human THP-1 cells. DO264 increases levels of chemokine (C-C motif) ligand 3 (CCL3), CCL4,...
| Schlagworte: | N-[1-[3-chloro-4-[2-chloro-4-(trifluoromethoxy)phenoxy]-2-pyridinyl]-4-piperidinyl]-N'-3-pyridinyl-thiourea |
| Anwendung: | Lysophosphatidylserine lipase ABHD12 inhibitor |
| CAS | 2301866-59-9 |
| MW: | 558.4 D |
ab 114,00 €
DO-264
Artikelnummer: TGM-T11069-1mg
Description: DO-264 is an inhibitor of autohydrolase structural domain 12 (ABHD12) (IC50: 11 nM) and an inhibitor of cellular LysoPS degradation that enhances LPS-induced phagocytosis. Target: Others. Smiles: FC(F)(F)Oc1ccc(Oc2ccnc(N3CCC(CC3)NC(=S)Nc3cccnc3)c2Cl)c(Cl)c1. References: Ogasawara D, et al. Selective...
| CAS | 2301866-59-9 |
| MW: | 558.4 D |
ab 49,00 €
