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NT-0796
Artikelnummer: Cay41237-1
NT-0796 is an inhibitor of the NOD-like receptor protein 3 (NLRP3) inflammasome and a prodrug form of NDT-19795. It selectively inhibits NLRP3 over NLR family CARD domain-containing protein 4 (NLRC4) at 3 nM, as well as a panel of 121 other receptors at 10 µM, but does inhibit the serotonin (5-HT) receptor subtype...
| Schlagworte: | (alphaR)-alpha-[[[(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)amino]carbonyl]oxy]-2-pyrimidinepropanoic acid, 1-methylethyl ester |
| Anwendung: | NLRP3 inflammasome inhibitor, NDT-19795 prodrug form |
| CAS | 2272917-13-0 |
| MW: | 409.5 D |
ab 153,00 €
NT-0796
Artikelnummer: TGM-T81637-50mg
Description: NT-0796 is a brain-permeable, potent, and selective inhibitor of the inflammasome NLRP3, inhibiting NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector. Target: NOD. Smiles: N(C(O[C@H](CC=1N=CC=CN1)C(OC(C)C)=O)=O)C2=C3C(=CC4=C2CCC4)CCC3
| Schlagworte: | NT0796, NT 0796 |
| Anwendung: | NLRP3 inflammasome inhibitor, NDT-19795 prodrug form |
| CAS | 2272917-13-0 |
| MW: | 409.48 D |
ab 186,00 €
