Zu "226878-01-9" wurden 2 Artikel gefunden!
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NPS 2390
Artikelnummer: Cay11989-10
Metabotropic glutamate receptors (mGluRs), mediate excitatory synaptic transmission in the central nervous system. Potent and selective antagonists of the type I mGluRs (mGluR1 and mGluR5) are of interest as novel therapeutics for the treatment of various CNS disorders, such as pain, epilepsy, and stroke. NPS 2390...
| Schlagworte: | N-tricyclo[3.3.1.13,7]dec-1-yl-2-quinoxalinecarboxamide |
| Anwendung: | mGluR1/mGluR5 antagonist |
| CAS | 226878-01-9 |
| MW: | 307.4 D |
ab 137,00 €
NEU
NPS2390
Artikelnummer: TGM-T8457-100mg
Description: NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively). Target: GluR. Smiles: O=C(NC12CC3CC(CC(C3)C1)C2)c1cnc2ccccc2n1. References: Peng X , Wei C , Li H Z , et al. NPS2390, a Selective Calcium-sensing...
| Anwendung: | mGluR1/mGluR5 antagonist |
| CAS | 226878-01-9 |
| MW: | 307.39 D |
ab 34,00 €
