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SGC-AAK1-1
Artikelnummer: TGM-T12885-100mg
Description: SGC-AAK1-1, a potent and selective inhibitor of AAK1 (AP2-associated kinase 1), has an IC50 of 270 nM and a Ki of 9 nM, and serves as a chemical probe. Target: AAK1 (AP2 associated kinase 1). Smiles: CCN(CC)S(=O)(=O)Nc1cccc(c1)-c1ccc2c(NC(=O)C3CC3)n[nH]c2c1. References: Agajanian MJ, et al. WNT...
| Anwendung: | AAK1 / BMP2K dual inhibitor |
| CAS | 2247894-32-0 |
| MW: | 427.52 D |
ab 40,00 €
SGC-AAK1-1
Artikelnummer: Cay41118-10
SGC-AAK1-1 is a dual inhibitor of AP2-associated protein kinase 1 (AAK1) and BMP2-inducible kinase (BMP2K, Kis = 9.1 and 17 nM, respectively). It is selective for AAK1 and BMP2K over cyclin G-associated kinase (GAK) and serine/threonine kinase 16 (STK16, Kis = 1,700 and 270 nM, respectively). See the Structural...
| Schlagworte: | N-[6-[3-[[(diethylamino)sulfonyl]amino]phenyl]-1H-indazol-3-yl]-cyclopropanecarboxamide |
| Anwendung: | AAK1 / BMP2K dual inhibitor |
| CAS | 2247894-32-0 |
| MW: | 427.5 D |
ab 107,00 €
