Zu "2247127-79-1" wurden 2 Artikel gefunden!
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Glutaminase-IN-1
Artikelnummer: Cay42339-1
An inhibitor of GLS1 (IC50 = 1 nM), selective for GLS1 over GDH (IC50 = >13 µM), inhibits the proliferation of A549, H22, Caki-1, and HCT116 cancer cells (IC50s = 0.017, 6.78, 0.019, and 0.009 µM, respectively), induces ROS production in A549 cells at 10 µM, decreases tumor weight in an HCT116 mouse xenograft model...
| Schlagworte: | GLS Inhibitor 1, GLS-IN-1, Glutaminase Inhibitor 1,... |
| Anwendung: | GLS1 inhibitor |
| CAS | 2247127-79-1 |
| MW: | 618.47 D |
ab 44,00 €
Glutaminase-IN-1
Artikelnummer: TGM-T11421-1mg
Description: Glutaminase-IN-1 (CB839 derivative), a novel 1,3,4-selenodiazepine inhibitor of the renal-type glutaminase (KGA) variant, exhibited antitumor activity in an aggressive H22 hepatocellular carcinoma xenograft model. Target: transporter. Smiles:...
| Schlagworte: | CB839 derivative |
| CAS | 2247127-79-1 |
| MW: | 618.47 D |
40,00 €
