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AB928
Artikelnummer: TGM-T14078-100mg
Description: AB928 is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist. It has immunomodulatory activity[1]. Target: Adenosine Receptor. Smiles: Cc1c(cccc1-c1cc(nc(N)n1)-c1cn(Cc2cccc(n2)C(C)(C)O)nn1)C#N. References: Seitz L, et al. Safety, tolerability, and pharmacology of AB928, a...
| Anwendung: | Antineoplastic, Adenosine A2 receptor antagonist |
| CAS | 2239273-34-6 |
| MW: | 426.47 D |
ab 46,00 €
AB-928
Artikelnummer: Cay31444-10
AB-928 is an adenosine A2A and A2B receptor dual antagonist. It inhibits the ability of adenosine (Cay-21232) to suppress activation of human CD4 or CD8 T cells, as well as monocyte-derived dendritic cells, in vitro. AB-928, alone or in combination with doxorubicin (Cay-15007), reduces tumor growth in an AT3-OVA...
| Schlagworte: | 3-[2-amino-6-[1-[[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]methyl]-1H-1,2,3-triazol-4-yl]-4-pyrimidinyl]-2-methyl-benzonitrile |
| Anwendung: | Adenosine A2A and A2B receptor dual antagonist |
| CAS | 2239273-34-6 |
| MW: | 426.5 D |
ab 161,00 €
