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YM-58483
YM-58483

Artikelnummer: Cay13246-1

Calcium release-activated calcium (CRAC) channels mediate sustained calcium influx in electrically non-excitable cells. CRAC channels are activated by the release of calcium from intracellular stores, as induced by inositol trisphosphate. CRAC channel activation is essential for the activation of leukocytes and the...
Schlagworte: BTP 2, N-[4-[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide
Anwendung: CRAC channel inhibitor
CAS 223499-30-7
MW: 421.3 D
ab 54,00 €
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YM-58483
YM-58483

Artikelnummer: TGM-T3651-5mg

Description: YM-58483 (BTP2) is a specific and effective inhibitor of CRAC channels and subsequent Ca2+ signals. Target: Calcium Channel. Smiles: Cc1nnsc1C(=O)Nc1ccc(cc1)-n1nc(cc1C(F)(F)F)C(F)(F)F. References: Ohga K, et al. Int Immunopharmacol. 2008, 8(13-14):1787-92.
Schlagworte: YM 58483, BTP2
Anwendung: CRAC channel inhibitor
CAS 223499-30-7
MW: 421.32 D
ab 30,00 €
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