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SZL P1-41
Artikelnummer: Cay26142-10
SZL P1-41 is an inhibitor of the Skp1-Cullin1-F-box (SCF) family protein Skp2. It inhibits the interaction between Skp2 and Skp1 to block Skp2 E3 ubiquitin ligase activity when used at a concentration of 5 µM. SZL P1-41 selectively inhibits Skp2 over Fbw7 and beta-TrCP E3 ubiquitin ligase activity in HEK293T cells....
| Schlagworte: | 3-(2-benzothiazolyl)-6-ethyl-7-hydroxy-8-(1-piperidinylmethyl)-4H-1-benzopyran-4-one |
| Anwendung: | Skp2 (FBXL1) inhibitor |
| CAS | 222716-34-9 |
| MW: | 420.5 D |
ab 180,00 €
SZL P1-41
Artikelnummer: TGM-T3317-100mg
Description: SZL P1-41, a skp2 inhibitor, can prevent assembly of Skp2-Skp1 complexes. It selectively suppresses Skp2 SCF E3 ligase activity but exhibits no effect on the activity of other SCF complexes. It also inhibits Skp2-mediated p27 and Akt ubiquitination in vivo and in vitro. It suppresses the survival of Y...
| Anwendung: | Skp2 (FBXL1) inhibitor |
| CAS | 222716-34-9 |
| MW: | 420.52 D |
ab 30,00 €
