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Dynarrestin
Artikelnummer: TGM-T15183-2mg
Description: Dynarrestin is a cytoplasmic dynein 1 and 2 aminothiazole inhibitor that reversibly inhibits dynein 1-driven microtubule sliding in vitro and intracellular dynein 1 and 2-dependent processes without affecting ATP hydrolysis and interfering with ciliogenesis . Target: Hedgehog/Smoothened. Smiles:...
| Anwendung: | Dynein inhibitor |
| CAS | 2222768-84-3 |
| MW: | 431.5 D |
ab 53,00 €
Dynarrestin
Artikelnummer: Cay35527-1
Dynarrestin is an inhibitor of dynein 1 and -2. It inhibits dynein 1-dependent microtubule gliding (IC50 = 5 µM) and dynein 2-dependent intraflagellar transport in mIMCD-3 inner medullary collecting duct cells when used at concentrations of 0.125 and 1.25 µM. Dynarrestin decreases the number of cells in metaphase,...
| Schlagworte: | 4-[4-(diethylamino)phenyl]-2-[(2,4-difluorophenyl)amino]-5-thiazolecarboxylic acid, ethyl ester |
| Anwendung: | Dynein inhibitor |
| CAS | 2222768-84-3 |
| MW: | 431.5 D |
ab 50,00 €
