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GW 8510
Artikelnummer: Cay43576-10
GW 8510 is an inhibitor of cyclin-dependent kinase 2 (Cdk2) and Cdk5 (IC50s = 3, 3, and 7 nM for Cdk2/cyclin E, Cdk2/cyclin A, and Cdk5/p25 complexes, respectively). It is selective for Cdk2 and Cdk5 over Cdk1/cyclin B, Cdk4/cyclin D, Cdk7/cyclin H, and Cdk9/cyclin T (IC50s = 49, 139, 317, and 543 nM, respectively)....
| Schlagworte: | 4-[[(6,7-dihydro-7-oxo-8H-pyrrolo[2,3-g]benzothiazol-8-ylidene)methyl]amino]-N-2-pyridinyl-benzenesulfonamide |
| Anwendung: | Cdk2 / Cdk5 inhibitor |
| CAS | 222036-17-1 |
| MW: | 449.5 D |
ab 157,00 €
GW8510
Artikelnummer: TGM-T24125-100mg
Description: GW8510 is a cyclin kinase 2 inhibitor. Target: Others. Smiles: C(NC1=CC=C(S(NC2=CC=CC=N2)(=O)=O)C=C1)=C3C=4C5=C(C=CC4NC3=O)N=CS5. References: Chen P, Wu JN, Shu Y, Jiang HG, Zhao XH, Qian H, Chen K, Lan T, Chen CG, Li J. Gemcitabine resistance mediated by ribonucleotide reductase M2 in lung squamous...
| Schlagworte: | GW-8510, GW 8510 |
| CAS | 222036-17-1 |
| MW: | 449.51 D |
ab 327,00 €
