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1-NM-PP1
Artikelnummer: Cay13330-10
1-NM-PP1 is a cell permeable inhibitor of kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. 1-NM-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over v-Src (IC50 = 4.2 nM versus 28...
| Schlagworte: | PP1 Analog II, 1-(1,1-dimethylethyl)-3-(1-naphthalenylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Anwendung: | Analog-sensitive kinase inhibitor |
| CAS | 221244-14-0 |
| MW: | 331.4 D |
ab 38,00 €
1-NM-PP1
Artikelnummer: TGM-T2153-100mg
Description: 1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors. Target: CDK, Serine/threonin kinase, Src. Smiles: CC(C)(C)n1nc(Cc2cccc3ccccc23)c2c(N)ncnc12. References: Larochelle S, et al. Requirements for Cdk7...
| Schlagworte: | PP1 Analog II, 1 nM-PP1 |
| CAS | 221244-14-0 |
| MW: | 331.41 D |
ab 41,00 €
