Zu "220904-99-4" wurden 2 Artikel gefunden!
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CID-25014542
Artikelnummer: Cay29837-10
A LRRK2 inhibitor (IC50 = 15 nM), selective for LRRK2 over a panel of 44 other kinases but does inhibit MAPK4 and Pim-2 at 1 µM, inhibits FLT3 at 10 µM, decreases the production of Abeta42 in a reporter assay using H4 cells overexpressing Abeta42 (IC50 = 15 µM), inhibits EGF-induced activation of MAPK in...
| Schlagworte: | 5-chloro-3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one |
| Anwendung: | LRRK2 inhibitor |
| CAS | 220904-99-4 |
| MW: | 429.49 D |
ab 97,00 €
Raf inhibitor 2
Artikelnummer: TGM-T4194-100mg
Description: Raf inhibitor 2 (CID 25014542) is novel inhibitor of Raf kinases. Target: Raf. Smiles: Oc1c(Br)cc(\C=C2/C(=O)Nc3ccc(Cl)cc23)cc1Br. References: Chen SH, et al. RAF inhibitor LY32009120 sensitizes RAS or BRAF mutant cancer to CDK4/6 inhibition by abemaciclib via superior inhibition of phospho-RB and...
| Schlagworte: | CID-25014542 , CID 25014542 , CID25014542 |
| Anwendung: | Raf inhibitor |
| CAS | 220904-99-4 |
| MW: | 429.49 D |
ab 38,00 €
