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7-Benzyloxy-4-(trifluoromethyl)coumarin
7-Benzyloxy-4-(trifluoromethyl)coumarin

Artikelnummer: Cay35721-10

7-Benzyloxy-4-(trifluoromethyl)coumarin (BFC) is a fluorogenic substrate for the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A. Upon enzymatic cleavage by CYP1A2 or CYP3A, 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) is released and its fluorescence can be used to quantify CYP1A2 and CYP3A activity. HFC displays...
Schlagworte: BFC, 7-(phenylmethoxy)-4-(trifluoromethyl)-2H-1-benzopyran-2-one
Anwendung: Fluorogenic CYP1A2 / CYP3A substrate
CAS 220001-53-6
MW: 320.3 D
ab 100,00 €
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7-Benzyloxy-4-trifluoromethycoumarin
7-Benzyloxy-4-trifluoromethycoumarin

Artikelnummer: CDX-B0299-M050

7-Benzyloxy-4-trifluoromethylcoumarin is a fluorescent substrate for cytochrome P450 family members CYP1A2, CYP3A4 and potentially others. Has been used in high-throughput screens in fluorometric p450 activity assays and is metabolized to the fluorescent metabolite 7-Hydroxy-4-trifluoromethylcoumarin (HFC) with...
Schlagworte: BFC
Anwendung: Fluoregenic CYP1A2 / CYP3A4 substrate
CAS 220001-53-6
MW: 320,3 D
ab 307,00 €
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