Zu "219580-11-7" wurden 2 Artikel gefunden!
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PD173074
Artikelnummer: TGM-T2642-100mg
Description: PD173074 is an effective FGFR1 inhibitor (IC50: 25 nM) and also inhibits VEGFR2 (IC50: 100-200 nM) in cell-free assays. The selectivity is higher ~1000-fold for FGFR1 than PDGFR and c-Src. Target: Apoptosis, EGFR, IGF-1R, Src, FGFR, VEGFR. Smiles:...
| CAS | 219580-11-7 |
| MW: | 523.67 D |
ab 37,00 €
PD 173074
Artikelnummer: Cay13032-5
The fibroblast growth factor receptors (FGFRs) are cell surface receptors with intrinsic tyrosine kinase activity, which is necessary for receptor activation and signal propagation. PD 173074 is a potent and selective inhibitor of FGFR tyrosine kinase activity, blocking autophosphorylation of FGFR1 with an IC50...
| Schlagworte: | N-[2-[[4-(diethylamino)butyl]amino]-6-(3,5-dimethoxyphenyl)pyrido[2,3-d]pyrimidin-7-yl]-N'-(1,1-dimethylethyl)-urea |
| Anwendung: | FGFR inhibitor |
| CAS | 219580-11-7 |
| MW: | 523.7 D |
ab 54,00 €
