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Heat Shock Protein Inhibitor I
Artikelnummer: Cay15395-1
Heat shock protein (Hsp) inhibitor I is a benzylidene lactam compound that prevents the synthesis of inducible Hsps Hsp105, Hsp72, and Hsp40. At 100 µM, it can inhibit the development of thermotolerance in COLO 320 DM cells. Its effects on thermotolerance have been studied in the context of clinical fractionated...
| Schlagworte: | Hsp Inhibitor I, KNK 437, 3-(1,3-benzodioxol-5-ylmethylene)-2-oxo-1-pyrrolidinecarboxaldehyde |
| Anwendung: | HSP105 / HSP72 / HSP40 induction inhibitor |
| CAS | 218924-25-5 |
| MW: | 245.2 D |
ab 73,00 €
KNK437
Artikelnummer: TGM-T2444-100mg
Description: KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40). Target: HSP. Smiles: O=CN1CCC(=Cc2ccc3OCOc3c2)C1=O. References: Yokota S, et al. Cancer Res. 2000, 60(11), 2942-2948.
| Schlagworte: | Heat Shock Protein Inhibitor I |
| CAS | 218924-25-5 |
| MW: | 245.23 D |
ab 33,00 €
