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CB-103
CB-103

Artikelnummer: Cay36293-1

CB-103 is an inhibitor of Notch signaling. It binds to the b-trefoil domain (BTD) of recombination signal binding protein for immunoglobulin kappa J region (RBPJ) and inhibits the assembly of the RBPJ-Notch intracellular domain (NICD) transcription complex. CB-103 inhibits ligand-induced Notch signaling in HeLa...
Schlagworte: 6-[4-(1,1-dimethylethyl)phenoxy]-3-pyridinamine
Anwendung: Notch signaling inhibitor
CAS 218457-67-1
MW: 242.3 D
ab 51,00 €
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NEU
CB-103
CB-103

Artikelnummer: TGM-T12246-100mg

Description: CB-103 is a orally active inhibitor of notch signaling pathway, with anti-tumor activity. Target: Gamma-secretase. Smiles: CC(C)(C)C1=CC=C(OC2=NC=C(N)C=C2)C=C1. References: Freddy Radtke, et al. Inhibitors of notch signalling pathway and use thereof in treatment of cancers. US9296682B2.
Anwendung: Notch signaling inhibitor
CAS 218457-67-1
MW: 242.32 D
ab 29,00 €
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