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PK68
Artikelnummer: Cay36653-10
PK68 is an inhibitor of receptor-interacting serine/threonine kinase 1 (RIPK1, IC50 = 90 nM). It is selective for RIPK1 over RIPK3 and a panel of 369 kinases at 1,000 nM. PK68 inhibits necroptosis induced by TNF-alpha, a Smac mimetic, and z-VAD in HT-29 colon cancer cells (EC50 = 23 nM). It reduces the number of...
| Schlagworte: | N-[5-[2-(acetylamino)-6-benzothiazolyl]-2-methyl-3-pyridinyl]-carbamic acid, cyclohexyl ester |
| Anwendung: | RIPK1 inhibitor |
| CAS | 2173556-69-7 |
| MW: | 424.5 D |
ab 216,00 €
PK68
Artikelnummer: TGM-T12493-100mg
Description: PK68 is an effective and selective inhibitor of type II receptor-interacting kinase 1 (RIPK1, IC50 = 90 nM). PK68 can be used for research on the treatment of inflammatory disorders and cancer metastasis. Target: Others, RIP kinase. Smiles: CC(=O)Nc1nc2ccc(cc2s1)-c1cnc(C)c(NC(=O)OC2CCCCC2)c1....
| Anwendung: | RIPK1 inhibitor |
| CAS | 2173556-69-7 |
| MW: | 424.52 D |
ab 74,00 €
