Zu "2170606-74-1" wurden 2 Artikel gefunden!
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DB2313
Artikelnummer: TGM-T9707-5mg
Description: DB2313 (Carboximidamide) is a potent transcription factor PU.1 inhibitor, IC50=14 nM. DB2313 disrupts the interaction of PU.1 with target gene promoters. DB2313 induces apoptosis of acute myeloid leukemia (AML) cells, and has anticancer effects. Target: Apoptosis. Smiles:...
| Schlagworte: | Carboximidamide |
| Anwendung: | PU.1 inhibitor |
| CAS | 2170606-74-1 |
| MW: | 708.83 D |
ab 49,00 €
DB2313 (hydrochloride)
Artikelnummer: Cay35021-1
DB2313 is an inhibitor of the transcription factor PU.1 (IC50 = 14 nM). Long-term exposure of DB2313 (300 nM) to Kit+/Sca-1+/Lin- hematopoietic stem progenitor cells (KSL-HSPCs) reduces colony formation. DB2313 (700 nM) decreases ovalbumin-induced reprogramming of isolated mouse neutrophils into antigen-presenting...
| Schlagworte: | 2,2'-[(2-fluoro-1,3-phenylene)bis(methyleneoxy-4,1-phenylene)]bis[N-(1-methylethyl)-1H-benzimidazole-6-carboximidamide |
| Anwendung: | PU.1 inhibitor |
| CAS | 2170606-74-1 |
| MW: | 708.8 D |
ab 39,00 €
