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MPT0G211
Artikelnummer: Cay43666-1
MPT0G211 is an inhibitor of histone deacetylase 6 (HDAC6, IC50 = 0. nM). It is selective for HDAC6 over HDAC1-5 (IC50s = 9. 12. 7. 4. and 3. µM, respectively), HDAC7-11 (IC50s = 0. 1. 1. 9. and 0. µM, respectively), and sirtuin 1 (SIRT1, IC50 = > 20 µM), as well as a panel of 97 kinases at 1 µM. MPT0G211 inhibits...
| Schlagworte: | N-hydroxy-4-[(8-quinolinylamino)methyl] benzamide |
| Anwendung: | HDAC6 inhibitor |
| CAS | 2151853-97-1 |
| MW: | 293.33 D |
ab 88,00 €
MPT0G211
Artikelnummer: TGM-T60616-100mg
Description: MPT0G211 is a highly selective and orally active HDAC6 inhibitor (IC50=0.291 nM) that has neuroprotective effects and has shown anti-metastatic activity in human breast cancer cells. MPT0G211 has 1,000 times more affinity for HDAC6 than other HDAC subtypes. MPT0G211 can cross the blood-brain barrier and...
| CAS | 2151853-97-1 |
| MW: | 293.32 D |
ab 93,00 €
