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1400W (hydrochloride)
1400W (hydrochloride)

Artikelnummer: Cay81520-5

1400W is a potent, selective inhibitor of iNOS. Using purified human iNOS, nNOS, and eNOS, 1400W exhibits Ki values of 7 nM, 2 µM, and 50 µM, respectively. In rat aortic rings it is at least 1,000-fold more potent against iNOS compared to eNOS. In mice bearing a murine mammary carcinoma, continuous infusion of 1400W...
Schlagworte: N-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide, dihydrochloride
Anwendung: iNOS inhibitor
CAS 214358-33-5
MW: 250.2 D
ab 73,00 €
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1400W . dihydrochloride
1400W . dihydrochloride

Artikelnummer: AG-CR1-0018-M005

A slow, tight binding and highly selective inhibitor of iNOS (inducible nitric oxide synthase/NOS II) (Kd &le, 7 nM), Weak and reversible inhibition of nNOS (neuronal nitric oxide synthase/NOS I) (Ki &le, 2) and eNOS (endothelial nitric oxide synthase/NOS III) (Ki &le, 50 µM), Inhibits tumor growth, Increases...
Schlagworte: N-(3-(Aminomethyl)benzyl)acetamidine . 2HCl
Anwendung: iNOS inhibitor
CAS 214358-33-5
MW: 250,3 D
ab 44,00 €
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