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GeA-69
Artikelnummer: TGM-T5399-100mg
Description: GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 µM in ITC assays). Target: PARP. Smiles: CC(=O)Nc1ccccc1-c1cccc2c3ccccc3[nH]c12. References: Schuller M, et al. Discovery of a Selective Allosteric Inhibitor Targeting Macrodomain 2 of...
| Anwendung: | PARP14 MD2 inhibitor |
| CAS | 2143475-98-1 |
| MW: | 300.35 D |
ab 37,00 €
GeA-69
Artikelnummer: AG-CR1-3706-M001
Off-white to light brownish solid. Soluble in DMSO (2mg/ml). Chemical. CAS: 2143475-98-1. Formula: C20H16N2O. MW: 300.4. Potent, selective, allosteric inhibitor of macrodomain 2 of poly-adenosine-diphosphate-ribose polymerase 14 (PARP-14 M2) (Kd=0.86µM, ITC (isothermal titration calorimetry) assay). PARP-14 is an...
| Schlagworte: | N-(2-(9H-Carbazol-1-yl)phenyl)acetamide |
| Anwendung: | PARP-14 M2 inhibitor |
| CAS | 2143475-98-1 |
| MW: | 300,4 D |
55,00 €
GeA-69
Artikelnummer: Cay39533-1
GeA-69 is an inhibitor of poly(ADP-ribose) polymerase 14 macrodomain 2 (PARP14 MD2). It binds to PARP14 MD2 (Kd = 860 nM) and inhibits PARP14 MD2 relocalization to the sites of DNA damage in U2OS cells when used at a concentration of 50 µM.Formal Name: N-[2-(9H-carbazol-1-yl)phenyl]-acetamide. CAS Number:...
| Schlagworte: | N-[2-(9H-carbazol-1-yl)phenyl]-acetamide |
| Anwendung: | PARP14 MD2 inhibitor |
| CAS | 2143475-98-1 |
| MW: | 300.4 D |
ab 36,00 €
