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FX-11
Artikelnummer: TGM-T15362-10mg
Description: FX-11 (LDHA Inhibitor FX11) is A potent, selective and competitive specific inhibitor of lactate dehydrogenase A (LDHA) with a Ki of 8 µM. FX-11 can activate PKM2 (pyruvate kinase M2). FX-11 can reduce ATP levels, induce oxidative stress and ROS production, and cause cell death. FX-11 appeared antitumor...
| Schlagworte: | LDHA Inhibitor FX11 |
| Anwendung: | LDH-A (lactate dehydrogenase-A) inhibitor |
| CAS | 213971-34-7 |
| MW: | 350.41 D |
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FX11
Artikelnummer: Cay38518-1
FX11 is an inhibitor of lactate dehydrogenase-A (LDH-A, Ki = 8 µM). It is selective for LDH-A over GAPDH (Ki = >300 µM). FX11 increases oxygen consumption and the production of reactive oxygen species (ROS), as well as induces cell death in P493-6 lymphoblastoid cells. In vivo, FX11 (42 µg/animal, i.p.) reduces...
| Schlagworte: | 2,3-dihydroxy-6-methyl-7-(phenylmethyl)-4-propyl-1-naphthalenecarboxylic acid |
| Anwendung: | LDH-A (lactate dehydrogenase-A) inhibitor |
| CAS | 213971-34-7 |
| MW: | 350.4 D |
ab 45,00 €
