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AB-680
AB-680

Artikelnummer: LKT-A040068.1

AB-680 is an inhibitor of CD73, which plays a key role in tumor growth, metastasis, and tumor-associated macrophage upregulation. SMILES: CC(C1=CC=CC=C1F)NC2=CC(=NC3=C2C=NN3C4C(C(C(O4)COP(=O)(CP(=O)(O)O)O)O)O)Cl
Schlagworte: AB680, Quemliclustat,...
Anwendung: CD73 inhibitor
CAS 2105904-82-1
MW: 580.83 D
ab 290,00 €
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AB-680
AB-680

Artikelnummer: TGM-T10216-5mg

Description: AB-680, a highly potent, reversible, and selective inhibitor of CD73 (an ectonucleotidase, Ki: 4.9 pM for hCD73) with anti-tumor activity, displays >10,000-fold selectivity over related ectonucleotidases CD39. Target: CD73. Smiles:...
CAS 2105904-82-1
MW: 580.82 D
ab 114,00 €
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AB-680
AB-680

Artikelnummer: Cay32798-1

AB-680 is an inhibitor of ecto-5'-nucleotidase, also known as CD73 (IC50 = 0.043 nM in CHO cells expressing the human enzyme). It is selective for ecto-5'-nucleotidase over nucleoside triphosphate diphosphorylase 1 (NTPDase 1), NTPDase 2, NTPDase 3, and NTPDase 8 (IC50s = >10 µM for all). AB-680 also inhibits...
Schlagworte: Quemliclustat,...
Anwendung: Ecto-5'-nucleotidase inhibitor
CAS 2105904-82-1
MW: 580.8 D
ab 106,00 €
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