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PF-06835919
Artikelnummer: Cay41842-1
PF-06835919 is an inhibitor of ketohexokinase C (KHK-C, IC50 = 10 nM). It is selective for KHK-C over KHK-A (IC50 = 170 nM) and a panel of 89 kinases, phosphatases, and receptors at 10 µM. PF-06835919 decreases the levels of fructose-1-phosphate in primary human- and rat hepatocytes (IC50s = 0.232 and 2.801 µM,...
| Schlagworte: | Ketohexokinase Inhibitor 1, (1alpha,5alpha,6alpha)-3-[2-[(2S... |
| Anwendung: | Ketohexokinase C (KHK-C) inhibitor |
| CAS | 2102501-84-6 |
| MW: | 356.3 D |
ab 136,00 €
Ketohexokinase inhibitor 1
Artikelnummer: TGM-T15654-100mg
Description: Ketohexokinase inhibitor 1 is a ketohexokinase inhibitor (IC50s: 8.4 nM and 66 nM for KHK-C and KHK-A, respectively). Target: Others. Smiles: C(C(O)=O)[C@@H]1[C@@]2([C@]1(CN(C2)C3=NC(=NC(C(F)(F)F)=C3)N4[C@@H](C)CC4)[H])[H]. References: SUBSTITUTED 3-AZABICYCLO[3.1.0]HEXANES AS KETOHEXOKI NASEINHIBI...
| Schlagworte: | PF-06835919 |
| Anwendung: | Ketohexokinase inhibitor |
| CAS | 2102501-84-6 |
| MW: | 356.34 D |
ab 184,00 €
