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Compound E
Compound E

Artikelnummer: Cay15579-1

gamma-Secretase is a multimeric aspartyl protease that regulates signaling pathways by proteolytically cleaving substrates, abrogating or releasing signaling molecules. Two well-known substrates are the carboxyl-terminal fragments (CTFs) of the receptor Notch, which has key roles in development, and that of amyloid...
Schlagworte: gamma-Secretase Inhibitor XXI,...
Anwendung: gamma-Secretase inhibitor
CAS 209986-17-4
MW: 490.5 D
ab 254,00 €
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Compound E
Compound E

Artikelnummer: AG-CR1-0081-M005

Cell permeable, potent, selective, non-transition state and non-competitive and gamma-secretase inhibitor. Notch processing inhibitor. Only weakly affects presenilinase activity.
Schlagworte: (2S)-2-([(3,5-Difluorophenyl)acetyl]amino)-N-[(3S)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]propanamide
Anwendung: gamma-secretase inhibitor
CAS 209986-17-4
MW: 490,5 D
ab 88,00 €
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