Zu "2095116-40-6" wurden 2 Artikel gefunden!
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BI-907828
Artikelnummer: Cay44353-1
BI-907828 is an inhibitor of the protein-protein interaction between p53 and murine double minute 2 (MDM2, IC50 = 2 nM in a cell-free assay). It is selective for the p53-MDM2 interaction over the p53-MDMX interaction (IC50 = 7,944 nM). BI-907828 selectively inhibits the proliferation of Colon-26 colon cancer cells,...
| Schlagworte: | Brigimadlin, (2'S,3'S,... |
| Anwendung: | p53-MDM2 protein-protein interaction inhibitor |
| CAS | 2095116-40-6 |
| MW: | 591,46 D |
ab 64,00 €
Brigimadlin
Artikelnummer: TGM-T69923-25mg
Description: Brigimadlin (BI 907828) is an orally active and highly potent E3 ubiquitin-protein ligase MDM2-p53 antagonist with antitumor activity.Brigimadlin can be used to study metastatic BTC, PDAC, lung adenocarcinoma, or bladder cancer. Target: MDM-2/p53, E1/E2/E3 Enzyme, Mdm2, p53. Smiles:...
| Schlagworte: | BI 907828 , BI907828 , BI-907828 |
| Anwendung: | Targets E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] (MDM2) |
| CAS | 2095116-40-6 |
| MW: | 591.46 D |
ab 152,00 €
