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TC13172
Artikelnummer: TGM-T17010-100mg
Description: TC13172 is an inhibitor of mixed lineage kinase domain-like protein (EC50: 2 nM for HT-29 cells). Target: Others. Smiles: Cn1c(nc2n(CC#Cc3cccc(O)c3)c(=O)n(C)c(=O)c12)S(C)(=O)=O
| CAS | 2093393-05-4 |
| MW: | 388.4 D |
ab 326,00 €
TC 13172
Artikelnummer: Cay31034-1
An inhibitor of MLKL and necroptosis, selective for MLKL over RIPK1 and RIPK3 at 10 µM, inhibits TSZ-induced necroptosis in HT-29 cells (EC50 = 2 nM), inhibits TSZ-induced oligomerization of MLKL and translocation of MLKL to the plasma membrane in HT-29 cells at 100 nM. Formulation: A solid. InChI:...
| Schlagworte: | 3,7-dihydro-3-[3-(3-hydroxyphenyl)-2-propyn-1-yl]-1,7-dimethyl-8-(methylsulfonyl)-1H-purine-2,6-dione |
| Anwendung: | MLKL / necroptosis inhibitor |
| CAS | 2093393-05-4 |
| MW: | 388.4 D |
ab 76,00 €
