Zu "208255-80-5" wurden 4 Artikel gefunden!
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DAPT
Artikelnummer: Cay13197-5
gamma-Secretase is a multi-subunit aspartyl protease that cleaves amyloid precursor protein (APP) and many other type 1 transmembrane proteins, including Notch, E-cadherin, and ErbB4. The proteolysis of APP by secretases produces beta amyloid (Abeta), a 39- to 42-amino acid peptide which forms the amyloid plaques...
| Schlagworte: | GSI-IX, N-[2S-(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-glycine, 1,1-dimethylethyl ester |
| Anwendung: | gamma-secretase inhibitor |
| CAS | 208255-80-5 |
| MW: | 432.5 D |
ab 88,00 €
DAPT
Artikelnummer: AG-CR1-0016-M005
Cell permeable gamma-secretase inhibitor (IC50 = 115 nM for total beta-amyloid, IC50 = 200 nM for beta-amyloid 1-42), Reduces Abeta levels in vivo, Blocks the proteolytic processing of neurotrophin receptor alike death domain protein (NRADD), Does not inhibit persenilinase, Notch processing inhibitor, Enhances...
| Schlagworte: | N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester |
| Anwendung: | gamma-secretase inhibitor |
| CAS | 208255-80-5 |
| MW: | 432,5 D |
ab 77,00 €
DAPT
Artikelnummer: TGM-T6202-5mg
Description: DAPT (LY-374973) is a gamma-secretase inhibitor that inhibits total Abeta and Abeta42 (IC50=115/200 nM) and is orally active. DAPT is also a Notch inhibitor. DAPT induces cell differentiation, autophagy and apoptosis. Target: Apoptosis, Autophagy, Gamma-secretase, Beta Amyloid. Smiles:...
| Schlagworte: | LY-374973, GSI-IX |
| Anwendung: | gamma-Secretase inhibitor |
| CAS | 208255-80-5 |
| MW: | 432.46 D |
ab 50,00 €
DAPT
Artikelnummer: LKT-D0260.1
gamma-Secretase inhibitor.
| Schlagworte: | GSI-IX |
| Anwendung: | gamma-Secretase inhibitor |
| CAS | 208255-80-5 |
| MW: | 432.47 D |
ab 94,00 €
